On the Simulation of Longitudinal Discrete Data with Specified Marginal Means and First-Order Antedependence

Matthew W. Guerra is in the Division of Biometrics III, OB, CDER, FDA, Silver Spring, MD 20993. Justine Shults is Associate Professor, Department of Biostatistics, University of Pennsylvania, Philadelphia, PA 19034 (E-mail: [email protected] and [email protected]). Disclaimer: This manuscript reflects the views of the authors and should not be construed to represent the FDA’s views or policies. Matthew Guerra began this work while he was a PhD student in the Department of Biostatistics at the University of Pennsylvania, and was supported by a grant from the National Cancer Institute (T32 CA93283). With permission from the journal, we note that an earlier version of this paper was submitted to The American Statistician on May 2, 2011, and a shorter version was tentatively accepted on May 28, 2013. The authors are also very grateful to their friend and mentor Professor Thomas Ten Have for suggesting that they work on this manuscript and dedicate this paper to his memory.